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Tesamorelin
Tesamorelin is a synthetic growth hormone releasing hormone (GHRH) analog administered as a once a day subcutaneous injection that stimulates the pituitary gland to increase the body’s natural production of growth hormone and insulin-like growth factor-1 (IGF-1). Tesamorelin differs from growth hormone itself by enhancing physiologic hormone secretion while preserving the body’s normal feedback mechanisms. It is approved for the reduction of excess visceral abdominal fat in adults. In two randomized, double blind, placebo controlled Phase 3 clinical trials, Tesamorelin significantly reduced visceral adipose tissue after 26 weeks of treatment, with continued therapy producing even greater reductions over one year. Ongoing research has also studied its role in improving nonalcoholic fatty liver disease (NAFLD).Participants who remained on tesamorelin for the full 52 weeks achieved approximately 18% reductions in visceral fat.
| Study Phase | Dosing Schedule |
| Weeks 1-26 | 2mg daily |
| Reconstitution Concentration | 1ml/10mg |
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